The citric acid cycle is one of the central logistical hub in our metabolism. It provides oxidative breakdown for organic substances, energy by releasing CO2 and H2O from Acetyl-CoA and so on. There are 10 basic steps to the cycle and its goal is to catalyze the condensation of Oxalacetate to Citrate. I will list the intermediates of this reaction and their respective enzymes , as well as their components : Citrate + Aconitase -> cis-Aconitate ( H20) cis-Aconitate + Aconitase -> Isocitrate ( H20) Isocitrate + Isocitrate-dehydrogenase -> Oxalsuccinate (NAD+, NADH) Oxalsuccinate + Isocitrate-dehydrogenase -> Alpha-ketoglutaric-acid (CO2) Alph a-ketoglutaric-acid + alpha-ketoglutarate-dehydrogenase-complex -> Succinyl-CoA (CoA, NAD+, CO2, NADH/H+) Succinyl-CoA + Succinyl-CoA-Synthase -> Succinate (GDP, ADP, GTP, ATP) Succinate...
Comments
Post a Comment