Posts

How To - Variance & Standard Deviation

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Hey Guys, today we do a quick intro on some basic terms and formulas that are used frequently in statistics - Mode or Modal Value, Middle Value, Median, Variance and the Standard Deviation We have a class of 8 Girls and 8 Boys , so a total of 16 kids . To get the Modal Value (m) and therefore represent the level of the whole class, we count how often each grade showed up - in our case 2 and 3 Next comes what probably everyone did at least once in school; calculate the class average or our Middle Value (a small X with a line over its top; sorry I can't write it out here .__. ) Using the Median is actually just being nit-picky, but good to know. In case your teacher breaks into your house in the middle of the night and wants to know... you will probably never use this one in your life For uneven : look for the middle number For even : look for the two middle numbers, sum them up and divide by 2 - that's your median The formula for Variance may look difficult at first,...

Metabolism - Biochemistry

Hey guys - although we entered into Biochemistry with the post about Glycolysis   I have a little summary here, what metabolism in general is going to be for me, during this semester. "Metabolism is the summed up lot of chemical reactions in our bodily cells, which we living organisms need to extract energy (in form of food and minerals) to perform actions, grow, heal or improve our physical self." Because energy seldom comes in the form our cells can use it right away, we need processes to breakdown bigger chunks - catabolic processes - i.e. Glycolysis (greek for sugar-splitting), I mean this example is awesome, because stuff is literally being broken down. And also energy is won from this reaction. On the other hand side, we are not just a machine that consumes and spits out product 1:1 Our body has the possibility to store energy for later on (yeah, shake that fat belly - don't worry it's potential energy is over 9000). ANYWAY. So called anabolic processes relea...

How To -Glycolysis - Biochemistry

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We are starting into a new semester and that means I am getting into Biochemistry II with you guys. Main Topic this semester will be the metabolism and from experience I can say, the most difficult part is to remember all the different steps in the many metabolic cycles our body needs to stay functioning. Glycolysis happens generally in 10 steps and is the process of breaking down glucose into smaller sugars The reaction itself takes place in the cytosol and after investing 2 ATP you get 4 ATP and 2 NADH First Step: Phosphorylation of Glucose Enzymes: Hexokinase aka Glucokinase Components: Glucose , ATP Hexokinase catalyses under exclusion of water the two components glucose + ATP , the product is now negatively charged and therefor caught in the cytosol Second Step: Isomerization Enzymes: Glucosephosphate-Isomerase Components: Glucose-6-Phosphate This reaction is essential for step four, because only from fructose you can derive two C3-molecules. Without isomerization, we would ...

Problems fixed!

So I managed to save my pages, books and about are fixed now^-^ It was a compiling mistake, which I don't know how got into there ._. but it's gone, for now.

The Evolution of Sex Part 1

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First of all, we still don't really know why sex developed in the first place. I mean for all the longtime singles out there, who desperately want a baby to give on their genes to the next generation (if you really just want to reproduce... uhm, maybe go and see a psychologist first?)  - things would be so much easier if they could just duplicate themselves. Voilá - perfect copy. But you see, the problem here is - it's just a copy. There is nothing new about it. This might work for now for you, but we live in an ever-changing world . Technology changes and if you don't adapt, you will find yourselves as clueless about gadgets just like your grandma when you first tried to explain to her how CSGO Players talk to each other via teamspeak in-game. But no innovation isn't the only problem. What if your genome suffers a deleterious mutation ? You can't go to one of your other clones, that didn't have that mutation and say "Oi, give me that, mine b...

How To - ELISA - Methods in Biochemistry

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That's a beautiful name, not the one of a young lady but rather stands for Enzyme Linked Immunosorbent Assay. This is a method very commonly used in labs and the mandatory practical class for Biochemistry.  It is based on an enzymatic interaction between antibodies and the kind of substance you want to detect; almost everything is possible - proteins like antigenes and viruses, hormones, and other organic material can be traced with this method. Below with the green color, you see what a finished ELISA looks like. Some of the s.c. Eppendorf tubes are heavier on the green, while others don't show any kind of color reachtion at all: In the following picture you can see how the process works as ELISA sandwhich method (the indirect identification of a substance): In picture 1 you see the green ' Y 's (representing protein-specific antibodies), they are fixed to a to a surface. Above them, the substance we are oh-so-interested in comes flying by. Next...

Current Projects

Hey there, coming week I have midterms for Methods of Biochemistry 2, simultaneously I'm reading "the search for the oldest stars" by Anna Frebel. I reached page 92 today, and so far I can say this book easily communicates Astrophysics in an understandable form. It is very interesting and not dry-written at all; my only concern lies in how much emphasis the author put on the work of female scientists and assistants in her book. Don't get me wrong, there is still a huge gap of recognition between the same amount of work men and women do, and it is of grave importance to remember who contributed something truly and not only because they were more accepted at the time (not only female assistants and scientists, but also jewish, who were prosecuted before and during WW2 i.e.) Miss Frebel seems to fangirl during the chapters which already I read, about science and especially the women of science. But that's just something I noticed. After all she dedicates this book to...